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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:dateCreated |
1985-11-14
|
| pubmed:abstractText |
A human hepatoma cell line (PLC/PRF/5) contains several copies of hepatitis B virus (HBV) DNA in integrated form and releases hepatitis B surface antigen (HBsAg) in the form of 22 nm particles in culture medium; studies of the supernatant fluid failed to provide evidence of the morphologically intact virion (Dane particle) or hepatitis B infectivity. In this paper we describe the effect of insulin on cell growth and HBsAg production by these cells; moreover we describe the insulin binding to specific cell membrane receptors. Data in our hands point to a different insulin binding related to different incubation conditions.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0301-5149
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
60
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
81-91
|
| pubmed:dateRevised |
2011-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2995179-Binding, Competitive,
pubmed-meshheading:2995179-Carcinoma, Hepatocellular,
pubmed-meshheading:2995179-Cell Division,
pubmed-meshheading:2995179-Cell Line,
pubmed-meshheading:2995179-Culture Media,
pubmed-meshheading:2995179-Hepatitis B virus,
pubmed-meshheading:2995179-Humans,
pubmed-meshheading:2995179-Insulin,
pubmed-meshheading:2995179-Liver Neoplasms,
pubmed-meshheading:2995179-Receptor, Insulin
|
| pubmed:year |
1985
|
| pubmed:articleTitle |
Effect of insulin on an insulin receptor of PLC/PRF/5 human hepatoma cell line.
|
| pubmed:publicationType |
Journal Article
|