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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1985-11-19
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pubmed:abstractText |
Plasma levels of beta-endorphin and ACTH were measured during and outside migraine attacks in 17 patients with common migraine and 11 patients with classic migraine. Specific radioimmunoassays for beta-endorphin and ACTH were used. The beta-endorphin assay did not cross-react with beta-lipotropin. In common migraine, median plasma beta-endorphin was 3.3 pmol/l (95% confidence limits: 2.5-4.0 pmol/l) during attacks and 2.9 (2.4-3.2) pmol/l in the headache-free period. In classic migraine, plasma beta-endorphin was 3.2 (1.4-4.3) pmol/l during attacks and 2.4 (1.1-3.6) pmol/l outside attacks. ACTH plasma levels were 15 (10.5-20) pmol/l during and 15.7 (13.4-17) pmol/l outside attacks in common migraine. In classic migraine, plasma ACTH was 16 (7-36) pmol/l and 12.3 (8-28) pmol/l respectively. No significant differences were found between attacks and headache-free periods in common or classic migraine. Accordingly, we could not add evidence to the theory of a dysfunction of the endogenous opioid system in migraine.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0333-1024
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
5
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
177-82
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pubmed:dateRevised |
2008-2-11
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pubmed:meshHeading |
pubmed-meshheading:2994887-Adrenocorticotropic Hormone,
pubmed-meshheading:2994887-Adult,
pubmed-meshheading:2994887-Aged,
pubmed-meshheading:2994887-Endorphins,
pubmed-meshheading:2994887-Humans,
pubmed-meshheading:2994887-Middle Aged,
pubmed-meshheading:2994887-Migraine Disorders,
pubmed-meshheading:2994887-beta-Endorphin
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pubmed:year |
1985
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pubmed:articleTitle |
Beta-endorphin and ACTH in plasma during attacks of common and classic migraine.
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pubmed:publicationType |
Journal Article
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