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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1992-4-20
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pubmed:abstractText |
The ultrastructure of four aldosterone secreting adenomas and of the adjacent zona glomerulosa has been described by the use of stereological techniques. Adenomatous cells (about 2800 microns 3 in volume) invariably displayed a striking abundance of lipid droplets, which occupied about 30% of the cytoplasm. Mitochondria prevalently contained tubulo-lamellar or lamellar cristae, but some cells exhibited organelles with vesicular cristae. Smooth endoplasmic reticulum (SER) was not very abundant. Small lipofuscin-pigment granules were frequently seen and in a few cells they were exceedingly numerous. Zona glomerulosa cells were smaller (about 950 microns 3 in volume) and possessed mitochondria with typical tubulo-lamellar cristae, a plentiful SER and few lipid droplets. They showed the ultrastructural features of elements actively engaged in steroid synthesis. The possible origin of aldosteronoma cells from the zona glomerulosa is discussed.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0213-3911
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
3
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
241-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2980230-Adenoma,
pubmed-meshheading:2980230-Adrenal Gland Neoplasms,
pubmed-meshheading:2980230-Adult,
pubmed-meshheading:2980230-Aldosterone,
pubmed-meshheading:2980230-Female,
pubmed-meshheading:2980230-Humans,
pubmed-meshheading:2980230-Microscopy, Electron,
pubmed-meshheading:2980230-Middle Aged,
pubmed-meshheading:2980230-Zona Glomerulosa
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pubmed:year |
1988
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pubmed:articleTitle |
An ultrastructural stereologic study of aldosterone secreting adrenal adenomas and of adjacent zona glomerulosa.
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pubmed:affiliation |
Department of Anatomy, University of Padua, Italy.
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pubmed:publicationType |
Journal Article
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