Linked Life Data

2926127

Source:http://linkedlifedata.com/resource/pubmed/id/2926127

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-4-21
pubmed:abstractText
We studied the distribution of the proteinase inhibitor antileukoprotease (ALP) and lysozyme (LSZ) in normal human tissues by use of an immunohistochemical technique. ALP could be demonstrated in a variety of healthy tissues, generated by secretory cells in lacrimal, respiratory, proximal digestive, and genital glands, but not in the urinary tract, endocrine glands, or the hematological system. In lung, part of the non-ciliated cell population in membranous bronchiolar epithelium, as well as in respiratory bronchioles, stained positively for the inhibitor. The distribution of ALP and LSZ was parallel in most but not all of the tissues examined. The distribution of ALP around most of the external orifices of the human body is discussed in relation to its possible local physiological role in defense against inflammatory reactions. The widespread parallel distribution of LSZ, a bacteriolytic agent, suggests a complementary role to ALP in local defense.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0022-1554
pubmed:author
pubmed:issnType
Print
pubmed:volume
37
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
493-8
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Tissue distribution of antileukoprotease and lysozyme in humans.
pubmed:affiliation
Department of Pulmonology, University Hospital, Lieden, The Netherlands.
pubmed:publicationType
Journal Article