Evidence that glutamic acid 49 of tryptophan synthase alpha subunit is a catalytic residue. Inactive mutant proteins substituted at position 49 bind ligands and transmit ligand-dependent to the beta subunit.

Source:http://linkedlifedata.com/resource/pubmed/id/2897961

J. Biol. Chem. 1988 Jun 25 263 18 8611-4

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2897961