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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
7
|
| pubmed:dateCreated |
1987-9-28
|
| pubmed:abstractText |
An HPLC assay for sulphapyridine is described. The use of the assay to measure sulphapyridine produced by the action of large bowel flora on 2 g of orally administered sulphasalazine as a means of assessing oro-colonic transit time is discussed. The assay is applied to show the action on oro-colonic transit time of a novel gastrokinetic agent BRL 24924 which brought about a 62.8% median reduction in transit time at a dose of 5 mg.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:month |
Jul
|
| pubmed:issn |
0174-4879
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
25
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
406-9
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2887521-Adult,
pubmed-meshheading:2887521-Benzamides,
pubmed-meshheading:2887521-Bicyclo Compounds, Heterocyclic,
pubmed-meshheading:2887521-Chromatography, High Pressure Liquid,
pubmed-meshheading:2887521-Gastrointestinal Motility,
pubmed-meshheading:2887521-Humans,
pubmed-meshheading:2887521-Male,
pubmed-meshheading:2887521-Sulfasalazine
|
| pubmed:year |
1987
|
| pubmed:articleTitle |
An HPLC assay for sulphapyridine in plasma and its use to assess small bowel transit time after the administration of sulphasalazine.
|
| pubmed:publicationType |
Journal Article
|