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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
1978-10-27
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pubmed:abstractText |
A dose-and-time related-effect of oral phenyltoloxamine citrate, a Class I, H1 antihistamine compound, has been demonstrated against allergen-induced wheal-and-erythema skin reactions among 10 adults with a diagnosis of allergic rhinitis and seasonal pollinosis. Clinical improvement in the existing symptoms of rhinorrhea, nasal obstruction, pruritus and sneezing, showed a significant correlation with the inhibition of reagin-mediated skin reactivity caused by phenytoloxamine. No adverse side effects were observed. It can be concluded that oral phenyltoloxamine citrate possesses antihistaminic properties and a range of safety which make it a useful agent for the symptomatic management of upper respiratory allergy.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0003-4738
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
41
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
140-4
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pubmed:dateRevised |
2005-11-17
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pubmed:meshHeading |
pubmed-meshheading:28684-Adolescent,
pubmed-meshheading:28684-Adult,
pubmed-meshheading:28684-Dose-Response Relationship, Drug,
pubmed-meshheading:28684-Ethanolamines,
pubmed-meshheading:28684-Histamine H1 Antagonists,
pubmed-meshheading:28684-Humans,
pubmed-meshheading:28684-Male,
pubmed-meshheading:28684-Mucous Membrane,
pubmed-meshheading:28684-Rhinitis, Allergic, Seasonal,
pubmed-meshheading:28684-Skin Tests
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pubmed:year |
1978
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pubmed:articleTitle |
Inhibition of cutaneous and mucosal allergy with phenyltoloxamine.
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pubmed:publicationType |
Journal Article
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