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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
1 Suppl
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pubmed:dateCreated |
1986-2-14
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pubmed:abstractText |
Monitoring plasma levels of tricyclic antidepressants (TCAs) can facilitate treatment response by providing objective guidelines for dosage adjustment. It provides a means of assessing the patient's compliance and ensuring the maintenance of an adequate medication trial while avoiding the complications of drug toxicity. The traditional dose-response method of medication adjustment depends on several assumptions that are not met in the case of TCAs, which makes plasma monitoring particularly useful for patients receiving most TCAs.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jan
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pubmed:issn |
0160-6689
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
47
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
24-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2867088-Adult,
pubmed-meshheading:2867088-Age Factors,
pubmed-meshheading:2867088-Antidepressive Agents, Tricyclic,
pubmed-meshheading:2867088-Antipsychotic Agents,
pubmed-meshheading:2867088-Barbiturates,
pubmed-meshheading:2867088-Brain Chemistry,
pubmed-meshheading:2867088-Child,
pubmed-meshheading:2867088-Depressive Disorder,
pubmed-meshheading:2867088-Dose-Response Relationship, Drug,
pubmed-meshheading:2867088-Drug Interactions,
pubmed-meshheading:2867088-Heart,
pubmed-meshheading:2867088-Humans,
pubmed-meshheading:2867088-Kinetics,
pubmed-meshheading:2867088-Middle Aged
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pubmed:year |
1986
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pubmed:articleTitle |
Tricyclic antidepressant plasma level monitoring: an improvement over the dose-response approach.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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