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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
1989-5-18
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pubmed:abstractText |
This is a detailed autopsy case of rare juvenile parkinsonism with dominant heredity. The patient displayed parkinsonian symptoms which began at the age of 24, and expired in a state of quadriplegia-in-flexion at 35. In the later stage, myoclonic jerks, epileptiform convulsions and dementia appeared. L-dopa was effective only in the early stages. The autopsy revealed severe degeneration and the formation of atypical Lewy bodies in the cerebral cortex, as well as typical lesions of idiopathic parkinsonism with a Lewy body formation in the brain stem. This case was considered to belong essentially to idiopathic parkinsonism. The pathology of juvenile parkinsonism is reviewed briefly.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0912-2036
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
42
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
265-76
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:2853802-Adult,
pubmed-meshheading:2853802-Brain,
pubmed-meshheading:2853802-Cerebral Cortex,
pubmed-meshheading:2853802-Female,
pubmed-meshheading:2853802-Humans,
pubmed-meshheading:2853802-Inclusion Bodies,
pubmed-meshheading:2853802-Levodopa,
pubmed-meshheading:2853802-Locus Coeruleus,
pubmed-meshheading:2853802-Microscopy, Electron,
pubmed-meshheading:2853802-Nerve Degeneration,
pubmed-meshheading:2853802-Neurons,
pubmed-meshheading:2853802-Parkinson Disease,
pubmed-meshheading:2853802-Substantia Nigra
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pubmed:year |
1988
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pubmed:articleTitle |
Clinical and neuropathological study of a familial case of juvenile parkinsonism.
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pubmed:affiliation |
National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Case Reports
|