Linked Life Data

2806664

Source:http://linkedlifedata.com/resource/pubmed/id/2806664

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
7
pubmed:dateCreated
1989-12-21
pubmed:abstractText
2-deoxy-D-glucose (2-DG) evokes an increase in the efferent discharge rate of the adrenal nerve in anesthetized rats and rabbits. A 63% increase in adrenal sympathetic nerve activity (adrSNA) occurred within 15 min after 125 mg/kg 2-DG administration in alert animals, no changes being revealed in the renal sympathetic nerve activity (renSNA), blood pressure (BP) or the heart rate (HR). Additional administration of 375 mg/kg 2-DG (cumulative dose 500 mg/kg) led to an over 120% increase in the adrSNA and the 20 mm Hg increase in the BP, whereas renSNA only increased by 30%. These results indicate that 2-DG-induced neuroglycopenia evokes highly differential changes in adrenal and renSNA in alert SHR rats. Whether this explains an obvious response of the BP in SHR to 2-DG, remains to be determined.
pubmed:language
rus
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jul
pubmed:issn
0015-329X
pubmed:author
pubmed:issnType
Print
pubmed:volume
75
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
899-903
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
[Differentiated changes in the activity of the sympathetic nerves induced by glycopenia in spontaneously hypertensive rats].
pubmed:publicationType
Journal Article, English Abstract