Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1989-6-13
|
pubmed:databankReference | |
pubmed:abstractText |
The nucleotide sequence of Tacaribe virus (TV) L gene was obtained from two sets of overlapping cDNA clones constructed by walking along the virus L RNA using two successive synthetic DNA primers. Analysis of the sequence indicated the existence of a unique long open reading frame in the viral complementary strand. The first in-phase AUG codon is in positions 31-33 from the 5' end of the viral complementary L RNA surrounded by a sequence favorable for initiation of protein synthesis. The open reading frame ends at positions 6661-6663. The predicted TV L protein is a 2210 amino acid long polypeptide with an estimated molecular weight of 251,942. Comparison of the amino acid sequence of TV L protein with peptide sequences predicted from L-derived cDNA clones of lymphocytic choriomeningitis virus shows an overall 42% of homology.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
0042-6822
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
170
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
40-7
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2718387-Amino Acid Sequence,
pubmed-meshheading:2718387-Arenaviridae,
pubmed-meshheading:2718387-Base Sequence,
pubmed-meshheading:2718387-Cloning, Molecular,
pubmed-meshheading:2718387-DNA, Viral,
pubmed-meshheading:2718387-Genes, Viral,
pubmed-meshheading:2718387-Lymphocytic choriomeningitis virus,
pubmed-meshheading:2718387-Molecular Sequence Data,
pubmed-meshheading:2718387-Molecular Weight,
pubmed-meshheading:2718387-Orthomyxoviridae,
pubmed-meshheading:2718387-Viral Proteins
|
pubmed:year |
1989
|
pubmed:articleTitle |
Tacaribe virus L gene encodes a protein of 2210 amino acid residues.
|
pubmed:affiliation |
Centro de Virologia Animal, Buenos Aires, Argentina.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|