Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1990-4-26
|
pubmed:abstractText |
In order to define an accurate assay for anti-adenovirus antibody detection, a recently developed ELISA was compared with IFA and CF. On 58 sera, the ELISA was more sensitive than both CF and IFA, which showed relative sensitivities of 63% and 94%, respectively. It was not possible to determine the exact specificity of the tests because of the lack of a gold standard. Furthermore, the ELISA was used to define the prevalence of adenovirus antibodies in 116 infants between 1 and 24 months old (mean 7.28). The data showed that maternal antibodies waned by the age of 5 to 6 months and that more than 80% of the children had been infected by adenoviruses by the age of 10 months.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:issn |
0036-4665
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
31
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
336-40
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:2697933-Adenoviridae,
pubmed-meshheading:2697933-Adenovirus Infections, Human,
pubmed-meshheading:2697933-Antibodies, Anti-Idiotypic,
pubmed-meshheading:2697933-Antibodies, Viral,
pubmed-meshheading:2697933-Complement Fixation Tests,
pubmed-meshheading:2697933-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:2697933-Fluorescent Antibody Technique,
pubmed-meshheading:2697933-Humans,
pubmed-meshheading:2697933-Immunity, Maternally-Acquired,
pubmed-meshheading:2697933-Immunoglobulin M,
pubmed-meshheading:2697933-Infant
|
pubmed:articleTitle |
Enzyme linked immunosorbent assay: determination of anti-adenovirus antibodies in an infant population.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|