| pubmed-article:2673083 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2673083 | lifeskim:mentions | umls-concept:C0543467 | lld:lifeskim |
| pubmed-article:2673083 | lifeskim:mentions | umls-concept:C0005411 | lld:lifeskim |
| pubmed-article:2673083 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:2673083 | pubmed:dateCreated | 1989-10-6 | lld:pubmed |
| pubmed-article:2673083 | pubmed:abstractText | One hundred thirty-one consecutive infants with biliary atresia were operated on during the 15-year period between 1973 and 1988. Six patients did not have biliary reconstruction because of advanced cirrhosis or transplant preference. The other 125 infants had excision of all nonpatent extrahepatic bile ducts; biliary drainage was provided by a gallbladder-common bile duct conduit in 14 patients and by a Roux-en-Y portoenterostomy in 111 infants (including the seven patients with correctable biliary atresia). The bilioenteric conduit was temporarily exteriorized and, for the past 2 years, a conduit intussusception valve was incorporated. Immediate postsurgical bile drainage was achieved in 103 infants (82%). Reoperation during the first 6 postoperative weeks restored bile flow in 14 of 18 infants who had shut down. Seventy-two patients (57%) had sustained (more than 1 year) relief of biliary obstruction. Postoperative morbidity was substantial. The six children not having corrective surgery died within 19 months. Three patients were lost to follow-up. Sixty-eight patients having Kasai's operation died, 55 from complications of liver disease, 1 from a coexisting malformation, and 12 after liver transplantation. Fifty-seven patients are alive, 13 by virtue of liver replacement, 9 with mild-to-moderate hepatic sequelae, and 35 (28%) with normal to near-normal liver function. Although none is considered "cured," the 35 children are anicteric, have normal growth and development, and participate in full school activities (including contact sports). Average follow-up is 85.8 months (range 1 to 15 years). | lld:pubmed |
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| pubmed-article:2673083 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2673083 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2673083 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2673083 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2673083 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2673083 | pubmed:issn | 0003-4932 | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:HallR JRJ | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:LillyJ RJR | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:SchroterG PGP | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:KarrerF MFM | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:GreenholzS... | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:StellinG PGP | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:WanekE AEA | lld:pubmed |
| pubmed-article:2673083 | pubmed:author | pubmed-author:Vasquez-Estev... | lld:pubmed |
| pubmed-article:2673083 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2673083 | pubmed:volume | 210 | lld:pubmed |
| pubmed-article:2673083 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2673083 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2673083 | pubmed:pagination | 289-94; discussion 294-6 | lld:pubmed |
| pubmed-article:2673083 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:2673083 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2673083 | pubmed:articleTitle | The surgery of biliary atresia. | lld:pubmed |
| pubmed-article:2673083 | pubmed:affiliation | Department of Surgery, University of Colorado School of Medicine, Denver 80262. | lld:pubmed |
| pubmed-article:2673083 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2673083 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2673083 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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