Linked Life Data

2649509

Source:http://linkedlifedata.com/resource/pubmed/id/2649509

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1989-5-24
pubmed:abstractText
The myelin-oligodendrocyte glycoprotein (MOG) is a minor component of central nervous system myelin. Using neonatal rat optic nerve oligodendrocyte cultures we have compared the development in vitro of MOG with galactocerebroside, myelin basic protein and 2' ,3'-cyclic-nucleotide 3'-phosphodiesterase. MOG appears on the surface of oligodendrocytes 1-2 days later than these other oligodendrocyte markers, suggesting that MOG may be a useful indicator of oligodendrocyte maturation. The relevance of these findings for investigating mechanisms of myelin injury in vitro and the role of oligodendrocyte damage in demyelinating disease is discussed.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
May
pubmed:issn
0165-5728
pubmed:author
pubmed:issnType
Print
pubmed:volume
22
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
169-76
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Myelin-oligodendrocyte glycoprotein (MOG) is a surface marker of oligodendrocyte maturation.
pubmed:affiliation
Department of Medicine, University of Wales College of Medicine, Cardiff, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't