Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1981-10-29
pubmed:abstractText
Synthetic filaments prepared from column-purified rabbit skeletal myosin by slow dialysis exhibit characteristic bipolar organization and 14-nm axial subunit spacing. Backbone substructure can be discerned in high resolution micrographs in the form of striations of 3--4-nm width and slight angular tilt from the direction of the filament axis. Filament backbone diameters vary over the population, although remaining relatively constant for a single filament. Approximately 25% of the filaments appear poorly stained and frayed, which may be due to collapse on the electron microscope grid. Optical diffraction studies reveal a 43-nm axial repeat as well as the 14.3-nm subunit repeat, indicating a structural homology with natural filaments. A model for synthetic filament aggregation is presented that is consistent with observations of backbone diameter variation, absence of bare zones, and the presence of fraying filaments.
pubmed:grant
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-1100851, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-1214296, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-1236853, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-13031633, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-13208680, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-14065312, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-140701, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-26379, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4269687, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4349760, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4399205, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4594144, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4769837, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-4817801, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-5476917, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-5586931, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-5970667, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-765477, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-881734, http://linkedlifedata.com/resource/pubmed/commentcorrection/263630-8842
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Sep
pubmed:issn
0006-3495
pubmed:author
pubmed:issnType
Print
pubmed:volume
27
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
423-32
pubmed:dateRevised
2009-11-19
pubmed:meshHeading
pubmed:year
1979
pubmed:articleTitle
Structural studies of synthetic filaments prepared from column-purified myosin.
pubmed:publicationType
Journal Article, Research Support, U.S. Gov't, P.H.S., Research Support, Non-U.S. Gov't