| pubmed-article:2606868 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2606868 | lifeskim:mentions | umls-concept:C0162429 | lld:lifeskim |
| pubmed-article:2606868 | lifeskim:mentions | umls-concept:C0236033 | lld:lifeskim |
| pubmed-article:2606868 | lifeskim:mentions | umls-concept:C0011155 | lld:lifeskim |
| pubmed-article:2606868 | lifeskim:mentions | umls-concept:C0441722 | lld:lifeskim |
| pubmed-article:2606868 | lifeskim:mentions | umls-concept:C0332162 | lld:lifeskim |
| pubmed-article:2606868 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:2606868 | pubmed:dateCreated | 1990-2-12 | lld:pubmed |
| pubmed-article:2606868 | pubmed:abstractText | The purpose was to study selected structural changes associated with the deficit in maximum specific force (N/cm2) during the early development of skeletal muscle hypertrophy. Ablation of gastrocnemius and plantaris muscles was performed bilaterally in 35-day-old rats (n = 41), and the soleus muscle was studied from days 1 to 30 thereafter. Compared with control muscles from age-matched unoperated rats (n = 48), muscle mass and cross-sectional area increased in parallel from 28 to 52% over the 30-day postoperative period. Specific force of hypertrophied muscle was depressed 38% at days 1 and 3, and by 28% from days 5 to 30 after synergistic muscle ablation compared with age-matched control values. Interstitial space was 38% greater than the control value of 20.4 +/- 1 microliters/100 mg at day 1 only. Protein concentration was depressed 15% for 7 days after the ablation operation, and connective tissue protein concentration was unchanged. The relative magnitude of increased mean fiber cross-sectional area was less than that of muscle mass until day 7 after ablation. Mononuclear cell infiltration in interfascicular spaces occurred from days 3 to 30 without light microscopic evidence of muscle fiber injury. Initial functional deficits are explained in part by an enlarged interstitial space and decreased protein concentration; later deficits are likely accounted for by intracellular changes. | lld:pubmed |
| pubmed-article:2606868 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2606868 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2606868 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2606868 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2606868 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2606868 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2606868 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:2606868 | pubmed:issn | 8750-7587 | lld:pubmed |
| pubmed-article:2606868 | pubmed:author | pubmed-author:WhiteT PTP | lld:pubmed |
| pubmed-article:2606868 | pubmed:author | pubmed-author:KandarianS... | lld:pubmed |
| pubmed-article:2606868 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2606868 | pubmed:volume | 67 | lld:pubmed |
| pubmed-article:2606868 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2606868 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2606868 | pubmed:pagination | 2600-7 | lld:pubmed |
| pubmed-article:2606868 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:meshHeading | pubmed-meshheading:2606868-... | lld:pubmed |
| pubmed-article:2606868 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2606868 | pubmed:articleTitle | Force deficit during the onset of muscle hypertrophy. | lld:pubmed |
| pubmed-article:2606868 | pubmed:affiliation | Department of Kinesiology, University of Michigan, Ann Arbor 48109-2214. | lld:pubmed |
| pubmed-article:2606868 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2606868 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2606868 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
