rdf:type |
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lifeskim:mentions |
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pubmed:issue |
8654
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pubmed:dateCreated |
1989-8-10
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pubmed:abstractText |
In a case-control study, consumption of dairy foods by 235 white women with epithelial ovarian cancer and by 239 control women, and activity of red blood cell galactose-1-phosphate uridyl transferase (transferase) in a subset of 145 cases and 127 controls were determined. Yogurt was consumed at least monthly by 49% of cases and 36% of controls. The mean transferase activity of cases was significantly lower than that of controls. When a ratio of lactose consumption to transferase (L/T) was calculated, cases had a mean L/T of 1.17 compared with 0.98 for controls; there was a highly significant trend for increasing ovarian cancer risk with increasing L/T ratio. Lactose consumption may be a dietary risk factor and transferase a genetic risk factor for ovarian cancer.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jul
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pubmed:issn |
0140-6736
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
8
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pubmed:volume |
2
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
66-71
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2567871-Adult,
pubmed-meshheading:2567871-Aged,
pubmed-meshheading:2567871-Contraceptives, Oral,
pubmed-meshheading:2567871-Dairy Products,
pubmed-meshheading:2567871-Dietary Carbohydrates,
pubmed-meshheading:2567871-Educational Status,
pubmed-meshheading:2567871-Female,
pubmed-meshheading:2567871-Galactose,
pubmed-meshheading:2567871-Humans,
pubmed-meshheading:2567871-Lactose,
pubmed-meshheading:2567871-Marriage,
pubmed-meshheading:2567871-Middle Aged,
pubmed-meshheading:2567871-Ovarian Neoplasms,
pubmed-meshheading:2567871-Parity,
pubmed-meshheading:2567871-Religion,
pubmed-meshheading:2567871-Risk Factors,
pubmed-meshheading:2567871-UTP-Hexose-1-Phosphate Uridylyltransferase
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pubmed:year |
1989
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pubmed:articleTitle |
Galactose consumption and metabolism in relation to the risk of ovarian cancer.
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pubmed:affiliation |
Brigham and Women's Hospital, Obstetrics and Gynecology Epidemiology Center, Boston, Massachusetts 02115.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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