| pubmed-article:2565265 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0221912 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0019588 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0055147 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0085170 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0085173 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0205178 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C1579762 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0009491 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C0205464 | lld:lifeskim |
| pubmed-article:2565265 | lifeskim:mentions | umls-concept:C1709059 | lld:lifeskim |
| pubmed-article:2565265 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:2565265 | pubmed:dateCreated | 1989-6-5 | lld:pubmed |
| pubmed-article:2565265 | pubmed:abstractText | In a double-blind study performed in 81 healthy volunteers, 10 mg cetirizine and 60 mg terfenadine given orally in a single administration significantly inhibited skin reactivity to histamine. Astemizole (10 mg) was completely ineffective. The inhibitory effect of cetirizine was potent and regular whereas 6/28 (21%) volunteers did not respond to terfenadine. The difference observed between cetirizine and terfenadine might be due to differences in the metabolism of the two drugs after administration: terfenadine is rapidly and extensively metabolized whereas cetirizine is directly active without the need for biotransformation and, indeed is poorly metabolized. | lld:pubmed |
| pubmed-article:2565265 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2565265 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2565265 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2565265 | pubmed:issn | 0300-0605 | lld:pubmed |
| pubmed-article:2565265 | pubmed:author | pubmed-author:EganR FRF | lld:pubmed |
| pubmed-article:2565265 | pubmed:author | pubmed-author:RihouxJ PJP | lld:pubmed |
| pubmed-article:2565265 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2565265 | pubmed:volume | 17 | lld:pubmed |
| pubmed-article:2565265 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2565265 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2565265 | pubmed:pagination | 24-7 | lld:pubmed |
| pubmed-article:2565265 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:meshHeading | pubmed-meshheading:2565265-... | lld:pubmed |
| pubmed-article:2565265 | pubmed:articleTitle | Pharmacological modulation of cutaneous reactivity to histamine: a double-blind acute comparative study between cetirizine, terfenadine and astemizole. | lld:pubmed |
| pubmed-article:2565265 | pubmed:affiliation | UCB sa, Chemin du Foriest, Braine l'Alleud, Belgium. | lld:pubmed |
| pubmed-article:2565265 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2565265 | pubmed:publicationType | Clinical Trial | lld:pubmed |
| pubmed-article:2565265 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:2565265 | pubmed:publicationType | Controlled Clinical Trial | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565265 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2565265 | lld:pubmed |
