Linked Life Data

2539793

Source:http://linkedlifedata.com/resource/pubmed/id/2539793

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1989-5-18
pubmed:abstractText
Two cases of sclerosing stromal tumor of the ovary (SST) are described. Immunohistochemical analysis of SSTs was performed using formalin-fixed and paraffin-embedded materials in comparison with thecofibromas and normal ovaries. The existence of desmin- and smooth-muscle actin-positive isolated spindle cells in SSTs and also in cortical stroma of the normal ovary was characteristically demonstrated, whereas such smooth-muscle-like cells were absent from six thecofibromas. Immunohistochemistry of desmin and smooth-muscle actin is useful in distinguishing SST from thecofibroma. Ultrastructural study further evidenced the presence of smooth-muscle-like cells in SSTs. In addition, we histochemically demonstrated heterogeneous cellular components in SSTs, including fibroblastic, thecalike, smooth muscle and endothelial cells. Hence, it is suggested that SST is derived from pluripotent immature stromal cells of the ovarian cortex.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0003-9985
pubmed:author
pubmed:issnType
Print
pubmed:volume
113
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
372-6
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Sclerosing stromal tumor of the ovary. Immunohistochemical and electron-microscopic demonstration of smooth-muscle differentiation.
pubmed:affiliation
Department of Pathology, Tokai University School of Medicine, Isehara, Japan.
pubmed:publicationType
Journal Article, Comparative Study, Case Reports