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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
5
|
| pubmed:dateCreated |
1989-10-3
|
| pubmed:abstractText |
The relationship between inferior vena cava diameter (VCD), collapse-index (CI) determined by echography, and alpha-human atrial natriuretic peptide (alpha-h-ANP) concentrations were studied in 19 chronic haemodialysis patients. A significant correlation was found between VCD and alpha-h-ANP before dialysis (r = 0.78; P less than 0.0001). No such correlation was found between CI, left atrial diameter and left ventricular end-diastolic diameter, and alpha-h-ANP values. In nine patients who according to vena cava indices were hypervolaemic before dialysis (group I), alpha-h-ANP concentrations were significantly greater than in ten normo- or hypovolaemic patients (group II): 392.8 +/- 134.1 pg/ml and 168.0 +/- 62.5 pg/ml respectively. Although the same amount of fluid was ultrafiltrated in both groups, alpha-h-ANP decreased significantly in group I only, whereas in group II the decrease was not significant: 392.8 +/- 134.1 to 185.2 +/- 81.7 (P less than 0.001); 168.0 +/- 62.5 to 130.0 +/- 59 respectively. After achieving normovolaemia alpha-h-ANP concentrations in patients with a mitral valve insufficiency grade I was doubled compared to normovolaemic patients without mitral valve insufficiency, suggesting that alpha-h-ANP release will also occur from the left atrium. In the latter group alpha-h-ANP values were approximately doubled compared to healthy controls. The highly significant correlation between VCD before dialysis and changes in alpha-h-ANP during dialysis with fluid removal underlines the value of vena cava diameter in estimating volume status.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0931-0509
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
4
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
382-6
|
| pubmed:dateRevised |
2004-11-17
|
| pubmed:meshHeading |
pubmed-meshheading:2528086-Adult,
pubmed-meshheading:2528086-Aged,
pubmed-meshheading:2528086-Atrial Natriuretic Factor,
pubmed-meshheading:2528086-Blood Pressure,
pubmed-meshheading:2528086-Blood Volume,
pubmed-meshheading:2528086-Cardiac Output,
pubmed-meshheading:2528086-Female,
pubmed-meshheading:2528086-Heart Rate,
pubmed-meshheading:2528086-Humans,
pubmed-meshheading:2528086-Kidney Failure, Chronic,
pubmed-meshheading:2528086-Male,
pubmed-meshheading:2528086-Middle Aged,
pubmed-meshheading:2528086-Renal Dialysis,
pubmed-meshheading:2528086-Ultrasonography,
pubmed-meshheading:2528086-Vena Cava, Inferior
|
| pubmed:year |
1989
|
| pubmed:articleTitle |
Plasma alpha-human atrial natriuretic peptide and volume status in chronic haemodialysis patients.
|
| pubmed:affiliation |
Department of Internal Medicine, University Hospital Maastricht, The Netherlands.
|
| pubmed:publicationType |
Journal Article
|