Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
1989-6-22
pubmed:abstractText
Pseudomonas aeruginosa often persists in ocular infections despite intensive antimicrobial therapy. In this study, gentamicin-resistant small colony variants (SCV) were selected in vitro from three gentamicin-susceptible Pseudomonas isolates by incubation with antibiotic. In the rat cornea, SCV were selected from two of these strains by administration of gentamicin either topically or intravenously. The selection of resistant variants may be a contributing factor in the persistence and reactivation frequently associated with ocular Pseudomonas infections.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
8756-3320
pubmed:author
pubmed:issnType
Print
pubmed:volume
5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
19-25
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1989
pubmed:articleTitle
Selection of gentamicin-resistant variants of Pseudomonas aeruginosa in the rat cornea.
pubmed:affiliation
Department of Ophthalmology, Flinders Medical Centre, Bedford Park, South Australia.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't