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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4919
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pubmed:dateCreated |
1989-9-27
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pubmed:abstractText |
Keratinocyte growth factor (KGF) is a human mitogen that is specific for epithelial cells. The complementary DNA sequence of KGF demonstrates that it is a member of the fibroblast growth factor family. The KGF transcript was present in stromal cells derived from epithelial tissues. By comparison with the expression of other epithelial cell mitogens, only KGF, among known human growth factors, has the properties of a stromal mediator of epithelial cell proliferation.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0036-8075
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
18
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pubmed:volume |
245
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
752-5
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pubmed:dateRevised |
2007-3-19
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pubmed:meshHeading |
pubmed-meshheading:2475908-Amino Acid Sequence,
pubmed-meshheading:2475908-Animals,
pubmed-meshheading:2475908-Base Sequence,
pubmed-meshheading:2475908-Cell Division,
pubmed-meshheading:2475908-Codon,
pubmed-meshheading:2475908-DNA,
pubmed-meshheading:2475908-Epithelial Cells,
pubmed-meshheading:2475908-Epithelium,
pubmed-meshheading:2475908-Fibroblast Growth Factor 10,
pubmed-meshheading:2475908-Fibroblast Growth Factor 7,
pubmed-meshheading:2475908-Fibroblast Growth Factors,
pubmed-meshheading:2475908-Fibroblasts,
pubmed-meshheading:2475908-Gene Expression Regulation,
pubmed-meshheading:2475908-Growth Substances,
pubmed-meshheading:2475908-Humans,
pubmed-meshheading:2475908-Mesoderm,
pubmed-meshheading:2475908-Mice,
pubmed-meshheading:2475908-Molecular Sequence Data,
pubmed-meshheading:2475908-Nucleic Acid Hybridization,
pubmed-meshheading:2475908-Oligonucleotide Probes,
pubmed-meshheading:2475908-RNA,
pubmed-meshheading:2475908-Sequence Homology, Nucleic Acid,
pubmed-meshheading:2475908-Skin,
pubmed-meshheading:2475908-Tissue Distribution,
pubmed-meshheading:2475908-Transcription, Genetic
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pubmed:year |
1989
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pubmed:articleTitle |
Human KGF is FGF-related with properties of a paracrine effector of epithelial cell growth.
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pubmed:affiliation |
Laboratory of Cellular and Molecular Biology, National Cancer Institute, Bethesda, MD 20892.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
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