| pubmed-article:2475189 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0021289 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0013935 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0005767 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0521457 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C1524075 | lld:lifeskim |
| pubmed-article:2475189 | lifeskim:mentions | umls-concept:C0043472 | lld:lifeskim |
| pubmed-article:2475189 | pubmed:issue | 4 | lld:pubmed |
| pubmed-article:2475189 | pubmed:dateCreated | 1989-9-25 | lld:pubmed |
| pubmed-article:2475189 | pubmed:abstractText | A sensitive and specific radioimmunoassay (RIA) for human embryonic zeta-globin chains was used to study normal fetal blood and newborn cord blood as well as cord blood from newborns with alpha-thalassemias. From 17 weeks until 37 weeks of gestation, zeta-globin chains were present in almost all fetal and cord blood samples (0.27% +/- 0.15% in samples of weeks 17 through 30; 0.14% +/- 0.11% in samples of weeks 31 through 37). zeta-Globin chains were present in greater than 80% of cord blood hemolysates from normal, full-term newborns (0.15% +/- 0.11%) as well as from 16 near-term newborns of diabetic mothers (0.13% +/- 0.13%). zeta-Globin chains were not detected in normal infants aged 3 months to 2 years. In cord blood hemolysates from alpha-thalassemic newborns, the levels of zeta-globin chain content varied from very high to undetectable levels. Gene mapping of the zeta-alpha-globin gene cluster was performed in 12 newborns in whom cord blood zeta-globin chains had been determined. Newborns who were carriers of alpha-thalassemia-1 due to the (--SEA/) deletion had very high levels of zeta-globin chains (greater than 1.5%). | lld:pubmed |
| pubmed-article:2475189 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:language | eng | lld:pubmed |
| pubmed-article:2475189 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:citationSubset | AIM | lld:pubmed |
| pubmed-article:2475189 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:2475189 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:2475189 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:2475189 | pubmed:issn | 0006-4971 | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:MentzerW CWC | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:MibashanR SRS | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:HiggsD RDR | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:PattersonMM | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:ChuiD HDH | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:EmburyS HSH | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:PerrineS PSP | lld:pubmed |
| pubmed-article:2475189 | pubmed:author | pubmed-author:IarocciT ATA | lld:pubmed |
| pubmed-article:2475189 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:2475189 | pubmed:volume | 74 | lld:pubmed |
| pubmed-article:2475189 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:2475189 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:2475189 | pubmed:pagination | 1409-14 | lld:pubmed |
| pubmed-article:2475189 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:meshHeading | pubmed-meshheading:2475189-... | lld:pubmed |
| pubmed-article:2475189 | pubmed:year | 1989 | lld:pubmed |
| pubmed-article:2475189 | pubmed:articleTitle | Human embryonic zeta-globin chains in fetal and newborn blood. | lld:pubmed |
| pubmed-article:2475189 | pubmed:affiliation | Department of Pathology, McMaster University School of Medicine, Hamilton, Ontario, Canada. | lld:pubmed |
| pubmed-article:2475189 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:2475189 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:2475189 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:2475189 | lld:pubmed |
