Linked Life Data

2469885

Source:http://linkedlifedata.com/resource/pubmed/id/2469885

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
1989-6-13
pubmed:abstractText
Two early steps of angiotensin II-induced biological response have been examined in cultured rat aortic, smooth muscle cells: (a) In addition to rapidly raising inositol 1,4,5-trisphosphate production, angiotensin II also induced the appearance of the isomer, inositol 1,3,4-trisphosphate, with similar kinetics: (b) Inositol 1,4,5-trisphosphate released calcium from an intracellular pool in electropermeabilized smooth muscle cells, in a concentration-dependent manner (EC50 = 0.25 microM). These data reinforce the concept of a critical role for agonist-induced polyphosphoinositide hydrolysis in the calcium-mediated responses of smooth muscle cells to angiotensin II.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0160-2446
pubmed:author
pubmed:issnType
Print
pubmed:volume
12 Suppl 5
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
S92-5
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Production of inositol trisphosphate isomers and release of intracellular calcium in cultured aortic vascular smooth muscle cells.
pubmed:affiliation
Division of Endocrinology, University Hospital, Geneva, Switzerland.
pubmed:publicationType
Journal Article, In Vitro, Research Support, Non-U.S. Gov't