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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
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pubmed:dateCreated |
1988-12-20
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pubmed:abstractText |
We studied the presence of beta-nerve growth factor (NGF) mRNA in the submandibular gland of the mouse by in situ hybridization using 35S-labeled prepro-beta-NGF antisense RNA. Female and male mice were studied at different stages of postnatal development, ranging from 3 to 12 weeks. Although NGF mRNA was detectable in the granular convoluted tubules of the submandibular gland in all the age and sex groups studied, the abundance of the signal dramatically increased after 5 weeks during the development of the submandibular gland. In addition, a conspicuous sexual dimorphism became increasingly apparent in the 6-, 7-, 10-, and 12-week-old animals, due to the remarkable development of the granular convoluted tubules in the adult male mouse, that expressed abundant NGF mRNA.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
0023-6837
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
59
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
625-30
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:2460695-Animals,
pubmed-meshheading:2460695-Female,
pubmed-meshheading:2460695-Male,
pubmed-meshheading:2460695-Mice,
pubmed-meshheading:2460695-Nerve Growth Factors,
pubmed-meshheading:2460695-Nucleic Acid Hybridization,
pubmed-meshheading:2460695-RNA,
pubmed-meshheading:2460695-RNA, Antisense,
pubmed-meshheading:2460695-RNA, Messenger,
pubmed-meshheading:2460695-Sex Factors,
pubmed-meshheading:2460695-Submandibular Gland
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pubmed:year |
1988
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pubmed:articleTitle |
In situ hybridization of nerve growth factor mRNA in the mouse submandibular gland.
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pubmed:affiliation |
Department of Pathology, Harbor-UCLA Medical Center, Torrance.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.,
Research Support, Non-U.S. Gov't
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