Linked Life Data

2455415

Source:http://linkedlifedata.com/resource/pubmed/id/2455415

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1988-8-8
pubmed:abstractText
The circadian rhythm of melatonin secretion of the pineal gland can be disturbed in a variety of clinical conditions and diseases including some psychic disorders. To study the rhythmic behaviour of melatonin secretion in atopic eczema (AE), melatonin serum levels were measured every 2 h, starting at 8 a.m. in 18 patients suffering from severe AE. In 6 patients exhibiting low serum levels of melatonin, the circadian melatonin rhythm was found to be abolished. In 8 patients a diminished nocturnal melatonin increase was observed compared with the controls (n = 40). Only 4 patients showed a normal secretion pattern of melatonin. The results provide some evidence of a dysfunction of the pineal gland in AE, possibly due to a partially reduced activity of the sympathetic nervous system being involved in the control of melatonin secretion.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0001-5555
pubmed:author
pubmed:issnType
Print
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
224-9
pubmed:dateRevised
2004-11-17
pubmed:meshHeading
pubmed:year
1988
pubmed:articleTitle
Alterations of melatonin secretion in atopic eczema.
pubmed:affiliation
Department of Dermatology, University of Erlangen-Nuernberg, Federal Republic of Germany.
pubmed:publicationType
Journal Article