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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
1987-8-7
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pubmed:abstractText |
The clinical and histopathological features of 12 female patients with Flegel's disease were studied. The onset of this dermatosis was delayed until adulthood. The eruption consisted of scaly papules 1-5 mm in diameter which developed principally on the lower legs, upper arms and pinnae. Histopathologically there were discrete foci of hyperkeratosis with some parakeratosis over an attenuated and partially spongiotic epidermis. A genetic influence in this disorder was suggested by its occurrence in sisters in two families and in a mother and daughter. Immunohistochemical and biochemical studies suggested that there is a disorder of keratinocyte proliferation in the disease.
|
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0007-0963
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
116
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pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
681-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:2439113-Adolescent,
pubmed-meshheading:2439113-Adult,
pubmed-meshheading:2439113-Epidermis,
pubmed-meshheading:2439113-Female,
pubmed-meshheading:2439113-Humans,
pubmed-meshheading:2439113-Hypertrophy,
pubmed-meshheading:2439113-Keratins,
pubmed-meshheading:2439113-Middle Aged,
pubmed-meshheading:2439113-Skin Diseases
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pubmed:year |
1987
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pubmed:articleTitle |
A clinicopathological study of Flegel's disease (hyperkeratosis lenticularis perstans).
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pubmed:publicationType |
Journal Article
|