pubmed-article:2353554 | pubmed:abstractText | The contractile effect of the analogue 1-deamino-1-carba-2-tyrosine (0-methyl)-oxytocin (carbetocin) on isolated strips from the human myometrium was compared with that of oxytocin. Neither oxytocin nor carbetocin affected contractile activity in strips from non-pregnant women, but both peptides stimulated contractile activity in strips from women at term pregnancy (2 x 10(-11) mol/l, and 10(-10) mol/l, respectively). Thus, carbetocin is almost as potent as oxytocin with regard to stimulating myometrial contractions at term. | lld:pubmed |