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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
4-6
|
| pubmed:dateCreated |
1990-7-16
|
| pubmed:abstractText |
A method for labeling monoclonal antimyosin antibodies with 66Ga is described. The radionuclide is a positron emitter (t1/2: 9.4h) produced by means of the 63Cu (4He, n) 66Ga reaction. Purification of the 66Ga from the copper target is described in detail. Monoclonal antimyosin antibodies are labeled with 66Ga at a high yield (99%) by transcomplexation from an acetate buffer with the diethylenetriamine pentaacetic acid (DTPA)-labeled antibody and preliminary evaluated in two dogs for imaging of myocardial necrosis by positron emission tomography.
|
| pubmed:language |
eng
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0340-6997
|
| pubmed:author | |
| pubmed:issnType |
Print
|
| pubmed:volume |
16
|
| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
|
| pubmed:pagination |
237-40
|
| pubmed:dateRevised |
2009-11-19
|
| pubmed:meshHeading |
pubmed-meshheading:2351172-Animals,
pubmed-meshheading:2351172-Antibodies, Monoclonal,
pubmed-meshheading:2351172-Dogs,
pubmed-meshheading:2351172-Gallium Radioisotopes,
pubmed-meshheading:2351172-Isotope Labeling,
pubmed-meshheading:2351172-Myocardial Infarction,
pubmed-meshheading:2351172-Myosins,
pubmed-meshheading:2351172-Pentetic Acid,
pubmed-meshheading:2351172-Radionuclide Generators,
pubmed-meshheading:2351172-Tomography, Emission-Computed
|
| pubmed:year |
1990
|
| pubmed:articleTitle |
Production of carrier-free 66Ga and labeling of antimyosin antibody for positron imaging of acute myocardial infarction.
|
| pubmed:affiliation |
Laboratory of Analytical Chemistry, Faculty of Pharmaceutical Sciences, University Hospital, Gent, Belgium.
|
| pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|