rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
6
|
pubmed:dateCreated |
1980-8-25
|
pubmed:abstractText |
All the eight 5'-di(tri)-3'-diphosphates of four common ribonucleosides were prepared by the enzymic pyrophosphoryl transfer catalysed by Streptomyces adephospholyticus ATP:nucleotide pyrophosphokinase (E.C.2.7.6.4) form dATP to the respective 5'-phosphates, and their effects on the translation of mRNAs by a wheat germ system in vitro were studied. (p) ppPupp decreased the total 14C-leucine incorporation directed by a rat liver mRNA whereas (p) ppPypp did not. With a silkworm pupa ovary mRNA, distinctly reverase results were obtained. Gel electrophoretic profiles of the translation products disclosed the mRNA species-specific stimulatory or inhibitory effects for each of the polyphosphates tested.
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pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
0261-3166
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
s151-4
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:232758-Adenine Nucleotides,
pubmed-meshheading:232758-Animals,
pubmed-meshheading:232758-Cytosine Nucleotides,
pubmed-meshheading:232758-Diphosphotransferases,
pubmed-meshheading:232758-Guanine Nucleotides,
pubmed-meshheading:232758-Guanosine Tetraphosphate,
pubmed-meshheading:232758-Kinetics,
pubmed-meshheading:232758-Liver,
pubmed-meshheading:232758-Nucleotides,
pubmed-meshheading:232758-Phosphotransferases,
pubmed-meshheading:232758-Plants,
pubmed-meshheading:232758-Protein Biosynthesis,
pubmed-meshheading:232758-RNA, Messenger,
pubmed-meshheading:232758-Rats,
pubmed-meshheading:232758-Streptomyces,
pubmed-meshheading:232758-Triticum,
pubmed-meshheading:232758-Uracil Nucleotides
|
pubmed:year |
1979
|
pubmed:articleTitle |
The specific, diverse effects of purine and pyrimidine nucleoside-5'-di(tri)-3'-diphosphates on the eucaryote translation system in vitro.
|
pubmed:publicationType |
Journal Article
|