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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
15
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pubmed:dateCreated |
1991-1-10
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pubmed:abstractText |
After a circa 10-year therapy with MC-insulin NOVO 12 diabetics were changed to the chromatographically purified insulins L-insulin S.N.C. and insulin S.N.C. of the nationally-owned enterprise Berlin-Chemie. 3 and 6 months, respectively, ago after the ambulatory change the patients were metabolically, immunologically, hormonally and clinically characterized. Profiles of blood glucose, value of glycaemia and HbA1 also lipid parameters, creatinine values, residual B-cell function, blood pressure and ophthalmologic state did not show any significant differences to the initial values after change to S.N.C.-insulins. Insulin-antibody level (9.5%-9.4%-9.7%) and insulin need (0.48 IU/kg-0.46 IU/kg-0.48 Iu/kg) also remained unchanged. Local reactions were not observed. Under the condition of a permanently good quality of the S.N.C.-insulins (purity and stability of the preparations) the application of chromatographically purified insulin of the firm Berlin-Chemie with comparable therapeutic success as in insulin MC NOVO is possible in a large part of the patients.
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pubmed:language |
ger
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Blood Glucose,
http://linkedlifedata.com/resource/pubmed/chemical/C-Peptide,
http://linkedlifedata.com/resource/pubmed/chemical/Delayed-Action Preparations,
http://linkedlifedata.com/resource/pubmed/chemical/Hemoglobin A, Glycosylated,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/insulin, neutral
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pubmed:status |
MEDLINE
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pubmed:month |
Aug
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pubmed:issn |
0044-2542
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
45
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
460-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:2247996-Adult,
pubmed-meshheading:2247996-Blood Glucose,
pubmed-meshheading:2247996-C-Peptide,
pubmed-meshheading:2247996-Delayed-Action Preparations,
pubmed-meshheading:2247996-Diabetes Mellitus, Type 1,
pubmed-meshheading:2247996-Female,
pubmed-meshheading:2247996-Hemoglobin A, Glycosylated,
pubmed-meshheading:2247996-Humans,
pubmed-meshheading:2247996-Insulin,
pubmed-meshheading:2247996-Male,
pubmed-meshheading:2247996-Middle Aged
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pubmed:year |
1990
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pubmed:articleTitle |
[Experiences with conversion from MC-insulin NOVO to L-insulin S.N.C. of insulin dependent diabetic patients].
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pubmed:affiliation |
Zentralstelle für Diabetes und Stoffwechselkrankheiten, Berlin.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Comparative Study,
English Abstract
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