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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
9
|
pubmed:dateCreated |
1990-11-19
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pubmed:abstractText |
Sixty-seven children under 2 years of age presenting with a classic clinical picture of coeliac disease with a severe small-intestinal mucosal lesion were investigated. All improved clinically and histologically on a gluten-free diet. During gluten challenge the mucosal damage recurred in 64 (95.5%) children, thus fulfilling the criteria for coeliac disease formulated by the European Society for Paediatric Gastroenterology and Nutrition. Three (4.5%) children had no mucosal relapse 2 years or more after return to a gluten-containing diet. These children were classified as having transient gluten intolerance. The low frequency of non-relapsers in the present study calls into question the practice of performing gluten challenge.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Sep
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pubmed:issn |
0036-5521
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
957-60
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:2218400-Biopsy,
pubmed-meshheading:2218400-Celiac Disease,
pubmed-meshheading:2218400-Female,
pubmed-meshheading:2218400-Glutens,
pubmed-meshheading:2218400-Humans,
pubmed-meshheading:2218400-Infant,
pubmed-meshheading:2218400-Intestinal Mucosa,
pubmed-meshheading:2218400-Intestine, Small,
pubmed-meshheading:2218400-Male
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pubmed:year |
1990
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pubmed:articleTitle |
Is gluten challenge necessary for the diagnosis of coeliac disease in young children?
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pubmed:affiliation |
Dept. of Paediatrics, Central Hospital, Danderyd, Sweden.
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pubmed:publicationType |
Journal Article
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