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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
10
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pubmed:dateCreated |
1990-12-20
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pubmed:abstractText |
The SF strain of human herpesvirus 6 (HHV-6SF) isolated from the saliva of a human immunodeficiency virus (HIV)-infected individual was shown to inhibit HIV type 1 (HIV-1) replication in both peripheral blood mononuclear cells and purified CD4+ lymphocytes. This suppression of HIV-1 replication led to decreased cytopathic effects of HIV-1 and prolonged survival of CD4+ cells in culture. Even low levels of HHV-6 added to peripheral blood mononuclear cells showed an inhibitory effect on HIV-1 replication. These results differ from those previously reported showing enhanced HIV-1 production following infection with another strain of HHV-6.
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pubmed:grant |
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-1970369,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-1975142,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2413137,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2416116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2431484,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2463490,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2564543,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-2911127,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-3095925,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-3157520,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-3546359,
http://linkedlifedata.com/resource/pubmed/commentcorrection/2172289-6328661
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Oct
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pubmed:issn |
0095-1137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
28
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2362-4
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
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pubmed:year |
1990
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pubmed:articleTitle |
Human herpesvirus 6 inhibits human immunodeficiency virus type 1 replication in cell culture.
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pubmed:affiliation |
Cancer Research Institute, School of Medicine, University of California, San Francisco 94143.
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pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, P.H.S.
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