Source:http://linkedlifedata.com/resource/pubmed/id/21718645
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| Predicate | Object |
|---|---|
| rdf:type | |
| lifeskim:mentions | |
| pubmed:issue |
6-7
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| pubmed:dateCreated |
2011-7-1
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| pubmed:abstractText |
Omega-6 polyunsaturated fatty acids (n-6 PUFA) are well known for their critical role in many physiological functions and reduce risks of cardiovascular disease (CVD). However, some argue that excessive consumption of n-6 PUFA may lead to adverse effects on health and therefore recommend reducing dietary n-6 PUFA intake or fixing an upper limit. Epidemiological studies show that n-6 PUFA dietary intake significantly lowers blood LDL-cholesterol levels. In addition, n-6 PUFA intake lower several cardiovascular risk factors such as blood pressure, inflammatory markers, haemostatic parameters and obesity. Data from prospective cohort and interventional studies converge towards a specific protective role of dietary n-6 PUFA intake, in particular linoleic acid, against CVD. In regards to studies examined in this narrative review, recommendation for n-6 PUFA intake above 5%, and ideally about 10% of total energy appears justified for the prevention of ischemic heart disease.
|
| pubmed:language |
fre
|
| pubmed:journal | |
| pubmed:citationSubset |
IM
|
| pubmed:chemical | |
| pubmed:status |
MEDLINE
|
| pubmed:issn |
0767-0974
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| pubmed:author | |
| pubmed:copyrightInfo |
© 2011 médecine/sciences - Inserm / SRMS.
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| pubmed:issnType |
Print
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| pubmed:volume |
27
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| pubmed:owner |
NLM
|
| pubmed:authorsComplete |
Y
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| pubmed:pagination |
614-8
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| pubmed:meshHeading |
pubmed-meshheading:21718645-Animals,
pubmed-meshheading:21718645-Cardiovascular Diseases,
pubmed-meshheading:21718645-Consensus,
pubmed-meshheading:21718645-Dietary Supplements,
pubmed-meshheading:21718645-Dose-Response Relationship, Drug,
pubmed-meshheading:21718645-Fatty Acids, Omega-6,
pubmed-meshheading:21718645-Humans,
pubmed-meshheading:21718645-Hyperlipidemias,
pubmed-meshheading:21718645-Inflammation,
pubmed-meshheading:21718645-Lipid Peroxidation,
pubmed-meshheading:21718645-Mice,
pubmed-meshheading:21718645-Nutrition Policy,
pubmed-meshheading:21718645-Nutritional Requirements,
pubmed-meshheading:21718645-Obesity,
pubmed-meshheading:21718645-Oxidative Stress,
pubmed-meshheading:21718645-Randomized Controlled Trials as Topic,
pubmed-meshheading:21718645-Species Specificity,
pubmed-meshheading:21718645-World Health
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| pubmed:articleTitle |
[N-6 fatty acids and cardiovascular health: dietary intake recommendations].
|
| pubmed:affiliation |
Unité de recherche d'épidémiologie nutritionnelle, UMR Inserm U557, INRA, CNAM, UP13, CRNH-Idf, Faculté SMBH, 74, rue Marcel Cachin, 93017 Bobigny, France. czernichow@uren.smbh.univ-paris13.fr
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| pubmed:publicationType |
Journal Article,
English Abstract
|