|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
6
|
|
pubmed:dateCreated |
2011-6-22
|
|
pubmed:databankReference |
|
|
pubmed:abstractText |
The melanocortin system plays an important role in energy homeostasis. Mice genetically deficient in the melanocortin-3 receptor gene have a normal body weight with increased body fat, mild hypophagia compared to wild-type mice. In humans, Thr6Lys and Val81Ile variants of the melanocortin-3 receptor gene (MC3R) have been associated with childhood obesity, higher BMI Z-score and elevated body fat percentage compared to non-carriers. The aim of this study is to assess the association in adults between allelic variants of MC3R with weight loss induced by energy-restricted diets.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-10951545,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-10965927,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-10973258,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-12532156,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-15189116,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-15394301,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-15769990,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-16123355,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-16274853,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-16434123,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-16469808,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-16871334,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-17043670,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-17192297,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-17413091,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-17578380,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-17639020,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-18155809,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-18231126,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-18239571,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-18296317,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-18382088,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19036988,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19079260,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19091795,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19244934,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19478790,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19541496,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19629057,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19656839,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-19812171,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-20032493,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-20110568,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-20144537,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-8932521,
http://linkedlifedata.com/resource/pubmed/commentcorrection/21695122-9276742
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1932-6203
|
|
pubmed:author |
pubmed-author:AstrupArneA,
pubmed-author:De la CruzRolandoR,
pubmed-author:GrauKatrineK,
pubmed-author:HansenTorbenT,
pubmed-author:HolstClausC,
pubmed-author:MacDonaldIanI,
pubmed-author:MaizAlbertoA,
pubmed-author:MartinezJ AlfredoJA,
pubmed-author:NUGENOB Consortium,
pubmed-author:NaranjoCarolinaC,
pubmed-author:OppertJean-MichelJM,
pubmed-author:PedersenOlufO,
pubmed-author:SantosJosé LJL,
pubmed-author:SarisWim H MWH,
pubmed-author:SorensenThorkild I ATI
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
6
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
e19934
|
|
pubmed:meshHeading |
pubmed-meshheading:21695122-Adipose Tissue,
pubmed-meshheading:21695122-Adult,
pubmed-meshheading:21695122-Alleles,
pubmed-meshheading:21695122-Animals,
pubmed-meshheading:21695122-Diet, Fat-Restricted,
pubmed-meshheading:21695122-Diet, Reducing,
pubmed-meshheading:21695122-Dietary Fats,
pubmed-meshheading:21695122-Energy Metabolism,
pubmed-meshheading:21695122-Female,
pubmed-meshheading:21695122-Genotype,
pubmed-meshheading:21695122-Humans,
pubmed-meshheading:21695122-Linkage Disequilibrium,
pubmed-meshheading:21695122-Male,
pubmed-meshheading:21695122-Mice,
pubmed-meshheading:21695122-Middle Aged,
pubmed-meshheading:21695122-Obesity,
pubmed-meshheading:21695122-Polymorphism, Single Nucleotide,
pubmed-meshheading:21695122-Receptor, Melanocortin, Type 3,
pubmed-meshheading:21695122-Waist Circumference,
pubmed-meshheading:21695122-Weight Loss,
pubmed-meshheading:21695122-Young Adult
|
|
pubmed:year |
2011
|
|
pubmed:articleTitle |
Allelic variants of melanocortin 3 receptor gene (MC3R) and weight loss in obesity: a randomised trial of hypo-energetic high- versus low-fat diets.
|
|
pubmed:affiliation |
Department of Nutrition, Diabetes and Metabolism, Pontificia Universidad Católica de Chile, Santiago, Chile.
|
