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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2011-6-17
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pubmed:abstractText |
Nitric oxide (NO), is a biological messenger molecule and a component of innate immunity, with important roles in the regulation of inflammation and in defense against bacterial biofilms. Polymorphisms in genes regulating NO production have the potential for a role in the development of chronic rhinosinusitis (CRS). The purpose of this study was to determine whether polymorphisms in genes regulating NO synthesis are associated with CRS.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
1945-8932
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
25
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
e49-54
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pubmed:dateRevised |
2011-11-10
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pubmed:meshHeading |
pubmed-meshheading:21679499-Adaptor Proteins, Signal Transducing,
pubmed-meshheading:21679499-Chronic Disease,
pubmed-meshheading:21679499-DNA Mutational Analysis,
pubmed-meshheading:21679499-Gene Frequency,
pubmed-meshheading:21679499-Genetic Association Studies,
pubmed-meshheading:21679499-Genetic Predisposition to Disease,
pubmed-meshheading:21679499-Genotype,
pubmed-meshheading:21679499-Humans,
pubmed-meshheading:21679499-Male,
pubmed-meshheading:21679499-Middle Aged,
pubmed-meshheading:21679499-Nasal Polyps,
pubmed-meshheading:21679499-Nitric Oxide Synthase Type I,
pubmed-meshheading:21679499-Polymorphism, Genetic,
pubmed-meshheading:21679499-Rhinitis,
pubmed-meshheading:21679499-Sinusitis
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pubmed:articleTitle |
Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis.
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pubmed:affiliation |
Department of Otolaryngology-head and Neck Surgery, Hôtel-Dieu de Montréal, Centre de Recherche du Centre Hospitalier de l'Université de Montreal, QC, Canada.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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