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pubmed-article:216308pubmed:abstractTextThe agent in wastewater sludge previously shown to reduce the heat required to inactivate reovirus (R. L. Ward and C. S. Ashley, Appl. Environ. Microbiol. 34:681--688, 1977) was "separated" from other sludge components and analyzed by infrared spectroscopy. The infrared spectrum of this material was quite similar to the spectra of commercial anionic detergents, and subsequent analyses of the fractionated sludge samples revealed that anionic detergents in sludge were copurified with the virucidal activity. Further measurements on the virucidal activities of specific detergents revealed that ionic detergents reduce the heat required to inactivate reovirus, that cationic detergents are more active than anionic, and that nonionic detergents are inactive. Several detergents were also shown to protect poliovirus and other enteroviruses against inactivation by heat. These results indicate that ionic detergents are the major component in wastewater sludge that reduce the thermal stability of reovirus and, in addition, that detergents are able to protect enteroviruses against heat.lld:pubmed
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pubmed-article:216308pubmed:articleTitleIdentification of detergents as components of wastewater sludge that modify the thermal stability of reovirus and enteroviruses.lld:pubmed
pubmed-article:216308pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:216308pubmed:publicationTypeComparative Studylld:pubmed
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