21602033

Source:http://linkedlifedata.com/resource/pubmed/id/21602033

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Predicate	Object
rdf:type	pubmed:Citation
lifeskim:mentions	umls-concept:C0007589, umls-concept:C0023779, umls-concept:C0033268, umls-concept:C0036505, umls-concept:C0231491, umls-concept:C0753910, umls-concept:C1511938
pubmed:issue	1
pubmed:dateCreated	2011-5-30
pubmed:abstractText	The melanocortin receptor-5 (MC5R) is present in human sebaceous glands, where it is expressed in differentiated sebocytes only. The targeted disruption of MC5R in mice resulted in reduced sebaceous lipid production and a severe defect in water repulsion.
pubmed:language	eng
pubmed:journal	http://linkedlifedata.com/resource/pubmed/journal/9011485
pubmed:citationSubset	IM
pubmed:chemical	http://linkedlifedata.com/resource/pubmed/chemical/Cyclic AMP, http://linkedlifedata.com/resource/pubmed/chemical/Flutamide, http://linkedlifedata.com/resource/pubmed/chemical/Hormone Antagonists, http://linkedlifedata.com/resource/pubmed/chemical/MUC1 protein, human, http://linkedlifedata.com/resource/pubmed/chemical/Mucin-1, http://linkedlifedata.com/resource/pubmed/chemical/Receptor, Melanocortin, Type 1, http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Melanocortin, http://linkedlifedata.com/resource/pubmed/chemical/melanocortin 5 receptor
pubmed:status	MEDLINE
pubmed:month	Jul
pubmed:issn	1873-569X
pubmed:author	pubmed-author:AnthonavageMichaelM, pubmed-author:EisingerMagdalenaM, pubmed-author:HuangQiulingQ, pubmed-author:LiWen-HwaWH, pubmed-author:PappasApostolosA, pubmed-author:RossettiDianneD, pubmed-author:SeibergMiriM, pubmed-author:ZhangLiL
pubmed:copyrightInfo	Copyright © 2011 Japanese Society for Investigative Dermatology. Published by Elsevier Ireland Ltd. All rights reserved.
pubmed:issnType	Electronic
pubmed:volume	63
pubmed:owner	NLM
pubmed:authorsComplete	Y
pubmed:pagination	23-32
pubmed:meshHeading	pubmed-meshheading:21602033-Administration, Cutaneous, pubmed-meshheading:21602033-Animals, pubmed-meshheading:21602033-Cell Differentiation, pubmed-meshheading:21602033-Cells, Cultured, pubmed-meshheading:21602033-Cyclic AMP, pubmed-meshheading:21602033-Dose-Response Relationship, Drug, pubmed-meshheading:21602033-Flutamide, pubmed-meshheading:21602033-Gene Expression Regulation, pubmed-meshheading:21602033-Hormone Antagonists, pubmed-meshheading:21602033-Humans, pubmed-meshheading:21602033-Lipid Metabolism, pubmed-meshheading:21602033-Male, pubmed-meshheading:21602033-Mice, pubmed-meshheading:21602033-Mice, SCID, pubmed-meshheading:21602033-Mucin-1, pubmed-meshheading:21602033-Receptor, Melanocortin, Type 1, pubmed-meshheading:21602033-Receptors, Melanocortin, pubmed-meshheading:21602033-Sebaceous Glands, pubmed-meshheading:21602033-Sebum, pubmed-meshheading:21602033-Skin Transplantation, pubmed-meshheading:21602033-Transplantation, Heterologous
pubmed:year	2011
pubmed:articleTitle	A melanocortin receptor 1 and 5 antagonist inhibits sebaceous gland differentiation and the production of sebum-specific lipids.
pubmed:affiliation	The Johnson & Johnson Skin Research Center, Consumer Product Worldwide, a Unit of Johnson & Johnson Consumer Companies, Inc. 199 Grandview Rd., Skillman, NJ 08558, USA.
pubmed:publicationType	Journal Article