Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
1990-6-5
pubmed:abstractText
Decreased levels of angiotensin converting enzyme plasma activity were found in systemic sclerosis. No relationship with clinical characteristics of the disease and increased von Willebrand factor antigen concentration (a widely accepted marker of endothelial injury) were statistically demonstrated. An inverse relationship between the reduced activity of the enzyme and erythrocyte sedimentation rate was detected (r = 0.410, p less than 0.05). We hypothesize that in systemic sclerosis, angiotensin converting enzyme activity might be affected by a decrease in endothelial production or by interference of circulating factors. Further studies are needed to determine if angiotensin converting enzyme activity could be used as a marker of endothelial injury in scleroderma.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0315-162X
pubmed:author
pubmed:issnType
Print
pubmed:volume
17
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
328-30
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1990
pubmed:articleTitle
Reduced angiotensin converting enzyme plasma activity in scleroderma. A marker of endothelial injury?
pubmed:affiliation
Institute of Clinical Medicine IV, University of Florence, Italy.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't