| pubmed-article:2151699 | pubmed:abstractText | Calcium-ATPase (Ca(2+)-ATPase) in the cells of the taste bud in the mouse vallate papilla was detected by the electron microscopic cytochemical procedure. In the mature taste bud, the enzyme was intensively located on the plasma membrane of various cell types and at the periphery of nerve fibers, but not in the subcellular organelles such as mitochondria, rough endoplasmic reticulum (rER) and the Golgi apparatus. Probably, plasma membrane Ca(2+)-ATPase plays primary role in determining the cytosolic Ca2+ concentration of the taste bud cell and nerve at a very low range about 10(-7) M. In the developing taste bud during the early postnatal period, on the other hand, CA(2+)-ATPase was apparently located in the lumen and cisternae of the rER. Golgi apparatus and small vesicles in the gustatory epithelial cells. These results suggest that Ca(2+)-ATPase synthesized in the rER passes through the Golgi apparatus to the plasma membrane, mediated by transport vesicles. | lld:pubmed |
