Source:http://linkedlifedata.com/resource/pubmed/id/21488653
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
5
|
pubmed:dateCreated |
2011-5-27
|
pubmed:abstractText |
Lithothamnin A (1) is a new bastadin-like metabolite and represents the first report of this class of molecules from the red alga Lithothamnion fragilissimum. Lithothamnin A contains several novel structural features that distinguish it from other bastadins. These unique structural features include novel aromatic substitution patterns and the presence of a meta-meta linkage between aromatic rings, in addition to the meta-para linkage seen in the bastadins. Lithothamnin A is modestly cytotoxic in a panel of six human tumor cell lines.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1520-6025
|
pubmed:author | |
pubmed:issnType |
Electronic
|
pubmed:day |
27
|
pubmed:volume |
74
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1275-80
|
pubmed:meshHeading |
pubmed-meshheading:21488653-Antineoplastic Agents,
pubmed-meshheading:21488653-Drug Screening Assays, Antitumor,
pubmed-meshheading:21488653-Halogenated Diphenyl Ethers,
pubmed-meshheading:21488653-Humans,
pubmed-meshheading:21488653-Molecular Structure,
pubmed-meshheading:21488653-Peptides, Cyclic,
pubmed-meshheading:21488653-Rhodophyta
|
pubmed:year |
2011
|
pubmed:articleTitle |
Lithothamnin A, the first bastadin-like metabolite from the red alga Lithothamnion fragilissimum.
|
pubmed:affiliation |
Molecular Targets Laboratory, Molecular Discovery Program, Center for Cancer Research, NCI-Frederick, Frederick, Maryland 21702-1202, United States.
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Intramural
|