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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
7
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pubmed:dateCreated |
2011-6-17
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pubmed:abstractText |
TAM receptors are expressed mainly by dendritic cells and macrophages in the immune system, and mice lacking TAM receptors develop systemic autoimmune diseases because of inefficient negative control of the cytokine signaling in those cells. This study aims to test the susceptibility of the TAM triple knockout (tko) mice to the retina-specific autoantigen to develop experimental autoimmune uveoretinitis (EAU).
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1552-5783
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
52
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
4239-46
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pubmed:dateRevised |
2011-9-21
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pubmed:meshHeading |
pubmed-meshheading:21467176-Animals,
pubmed-meshheading:21467176-Autoantigens,
pubmed-meshheading:21467176-Autoimmune Diseases,
pubmed-meshheading:21467176-Dendritic Cells,
pubmed-meshheading:21467176-Disease Models, Animal,
pubmed-meshheading:21467176-Disease Susceptibility,
pubmed-meshheading:21467176-Eye Proteins,
pubmed-meshheading:21467176-Female,
pubmed-meshheading:21467176-Lymphocyte Activation,
pubmed-meshheading:21467176-Mice,
pubmed-meshheading:21467176-Mice, Knockout,
pubmed-meshheading:21467176-Retina,
pubmed-meshheading:21467176-Retinal Diseases,
pubmed-meshheading:21467176-Retinol-Binding Proteins,
pubmed-meshheading:21467176-T-Lymphocytes
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pubmed:year |
2011
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pubmed:articleTitle |
TAM receptor knockout mice are susceptible to retinal autoimmune induction.
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pubmed:affiliation |
Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, Kentucky 40202, USA.
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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