Linked Life Data

21372560

Source:http://linkedlifedata.com/resource/pubmed/id/21372560

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pubmed-article:21372560pubmed:abstractTextThe proinflammatory cytokine S100A12 (also known as EN-RAGE) is associated with cardiovascular morbidity and mortality in hemodialysis patients. In the current study, we tested the hypothesis that S100A12 expressed in vascular smooth muscle in nonatherosclerosis-prone C57BL/6J mice on normal rodent chow diet, but exposed to the metabolic changes of chronic kidney disease (CKD), would develop vascular disease resembling that observed in patients with CKD.lld:pubmed
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pubmed-article:21372560pubmed:authorpubmed-author:GawdzikJoseph...lld:pubmed
pubmed-article:21372560pubmed:copyrightInfoCopyright © 2011 S. Karger AG, Basel.lld:pubmed
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pubmed-article:21372560pubmed:articleTitleVascular remodeling and arterial calcification are directly mediated by S100A12 (EN-RAGE) in chronic kidney disease.lld:pubmed
pubmed-article:21372560pubmed:affiliationSections of Cardiology, Department of Medicine, University of Chicago, IL 60637, USA.lld:pubmed
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pubmed-article:21372560pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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