Source:http://linkedlifedata.com/resource/pubmed/id/21370258
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
4
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pubmed:dateCreated |
2011-4-20
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pubmed:abstractText |
Levodopa initially provides good symptomatic control of the symptoms of Parkinson's disease, but motor complications often develop after long-term use. Other classes of antiparkinsonian drugs including dopamine agonists, catechol-O-methyl transferase inhibitors, or monoamine oxidase type B inhibitors are then added as adjuvant therapy. It is unclear whether one class of drug is more effective than another. This meta-analysis evaluates the comparative benefits and risks of these agents as adjuvant treatment in Parkinson's disease patients with motor complications.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
1531-8257
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2011 Movement Disorder Society.
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pubmed:issnType |
Electronic
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pubmed:volume |
26
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
587-98
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pubmed:meshHeading |
pubmed-meshheading:21370258-Adjuvants, Pharmaceutic,
pubmed-meshheading:21370258-Antiparkinson Agents,
pubmed-meshheading:21370258-Clinical Trials as Topic,
pubmed-meshheading:21370258-Disability Evaluation,
pubmed-meshheading:21370258-Enzyme Inhibitors,
pubmed-meshheading:21370258-Humans,
pubmed-meshheading:21370258-Levodopa,
pubmed-meshheading:21370258-Parkinson Disease,
pubmed-meshheading:21370258-Treatment Outcome
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pubmed:year |
2011
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pubmed:articleTitle |
Meta-analysis of the comparative efficacy and safety of adjuvant treatment to levodopa in later Parkinson's disease.
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pubmed:affiliation |
Birmingham Clinical Trials Unit, College of Medical & Dental Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom. r.l.harrison@bham.ac.uk
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pubmed:publicationType |
Journal Article,
Review,
Research Support, Non-U.S. Gov't,
Meta-Analysis
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