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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
5
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pubmed:dateCreated |
2011-4-21
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pubmed:abstractText |
The postprandial metabolism of dietary fats results in the production of apolipoprotein B-48 (apoB48)-containing triglyceride-rich lipoproteins (TRLs), which cause rapid receptor-mediated macrophage lipid engorgement via the apoB48 cell surface receptor (apoB48R). Monocytes circulate together with apoB48-containing TRLs in the postprandial bloodstream and may start accumulating lipids even before their migration to tissues and differentiation to macrophages.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1938-3207
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
918-25
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pubmed:meshHeading |
pubmed-meshheading:21367954-Adult,
pubmed-meshheading:21367954-Cross-Over Studies,
pubmed-meshheading:21367954-Dietary Fats,
pubmed-meshheading:21367954-Humans,
pubmed-meshheading:21367954-Hypertriglyceridemia,
pubmed-meshheading:21367954-Kinetics,
pubmed-meshheading:21367954-Lipid Metabolism,
pubmed-meshheading:21367954-Lipids,
pubmed-meshheading:21367954-Male,
pubmed-meshheading:21367954-Monocytes,
pubmed-meshheading:21367954-RNA, Messenger,
pubmed-meshheading:21367954-Receptors, Lipoprotein,
pubmed-meshheading:21367954-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:21367954-Single-Blind Method,
pubmed-meshheading:21367954-Transcriptional Activation,
pubmed-meshheading:21367954-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
A high-fat meal promotes lipid-load and apolipoprotein B-48 receptor transcriptional activity in circulating monocytes.
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pubmed:affiliation |
Laboratory of Cellular and Molecular Nutrition, Instituto de la Grasa, Seville, Spain.
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pubmed:publicationType |
Journal Article,
Clinical Trial,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't
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