Source:http://linkedlifedata.com/resource/pubmed/id/21177075
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2-3
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pubmed:dateCreated |
2011-2-1
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pubmed:abstractText |
Recent studies have provided much needed data on the probability of seizure remission among adults with chronic intractable epilepsy treated medically. Here we provide an extended follow-up to our earlier study in order to provide a more comprehensive picture of long-term prognosis in this patient population during medical treatment. The prevalence cohort was followed for two outcomes-complete seizure remission for ? 12 months and subsequent seizure relapse among those attaining a seizure remission. The study outcomes were estimated using Kaplan-Meier analysis. We found that the probability of attaining a ? 12 months of complete seizure freedom to be approximately 3-4% per year through 8 years of follow-up. By year 5 since the start of seizure remission, the cumulative probability of seizure relapse was 81%, although only half of the patients with seizure relapse went on to experience their previous seizure frequency.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1872-6844
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pubmed:author | |
pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
93
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
115-9
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pubmed:meshHeading |
pubmed-meshheading:21177075-Adult,
pubmed-meshheading:21177075-Anticonvulsants,
pubmed-meshheading:21177075-Drug Resistance,
pubmed-meshheading:21177075-Endpoint Determination,
pubmed-meshheading:21177075-Epilepsy,
pubmed-meshheading:21177075-Female,
pubmed-meshheading:21177075-Follow-Up Studies,
pubmed-meshheading:21177075-Humans,
pubmed-meshheading:21177075-Kaplan-Meier Estimate,
pubmed-meshheading:21177075-Male,
pubmed-meshheading:21177075-Middle Aged,
pubmed-meshheading:21177075-Proportional Hazards Models,
pubmed-meshheading:21177075-Recurrence,
pubmed-meshheading:21177075-Remission, Spontaneous,
pubmed-meshheading:21177075-Seizures
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pubmed:year |
2011
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pubmed:articleTitle |
Seizure remission in adults with long-standing intractable epilepsy: an extended follow-up.
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pubmed:affiliation |
Department of Neurology, Columbia University, New York, NY, United States. hc323@columbia.edu
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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