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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2011-5-2
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pubmed:abstractText |
There is substantial evidence that cognitive deficits and brain structural abnormalities are present in patients with Bipolar Disorder (BD) and in their first-degree relatives. Previous studies have demonstrated associations between cognition and functional outcome in BD patients but have not examined the role of brain morphological changes. Similarly, the functional impact of either cognition or brain morphology in relatives remains unknown. Therefore we focused on delineating the relationship between psychosocial functioning, cognition and brain structure, in relation to disease expression and genetic risk for BD.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
1573-2517
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pubmed:author |
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pubmed:copyrightInfo |
Copyright © 2010 Elsevier B.V. All rights reserved.
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pubmed:issnType |
Electronic
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
413-20
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pubmed:meshHeading |
pubmed-meshheading:21112093-Adolescent,
pubmed-meshheading:21112093-Adult,
pubmed-meshheading:21112093-Aged,
pubmed-meshheading:21112093-Attention,
pubmed-meshheading:21112093-Bipolar Disorder,
pubmed-meshheading:21112093-Brain,
pubmed-meshheading:21112093-Cross-Sectional Studies,
pubmed-meshheading:21112093-Executive Function,
pubmed-meshheading:21112093-Family,
pubmed-meshheading:21112093-Female,
pubmed-meshheading:21112093-Genetic Predisposition to Disease,
pubmed-meshheading:21112093-Humans,
pubmed-meshheading:21112093-Intelligence,
pubmed-meshheading:21112093-Intelligence Tests,
pubmed-meshheading:21112093-Magnetic Resonance Imaging,
pubmed-meshheading:21112093-Male,
pubmed-meshheading:21112093-Memory,
pubmed-meshheading:21112093-Middle Aged,
pubmed-meshheading:21112093-Neuropsychological Tests,
pubmed-meshheading:21112093-Organ Size,
pubmed-meshheading:21112093-Young Adult
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pubmed:year |
2011
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pubmed:articleTitle |
The impact of general intellectual ability and white matter volume on the functional outcome of patients with Bipolar Disorder and their relatives.
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pubmed:affiliation |
Institute of Psychiatry, King's College London, King's Health Partners, London, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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