Source:http://linkedlifedata.com/resource/pubmed/id/21110847
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:dateCreated |
2010-12-21
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pubmed:abstractText |
DUX4 is causally involved in the molecular pathogenesis of the neuromuscular disorder facioscapulohumeral muscular dystrophy (FSHD). It has previously been proposed to have arisen by retrotransposition of DUXC, one of four known intron-containing DUX genes. Here, we investigate the evolutionary history of this multi-member double-homeobox gene family in eutherian mammals.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
1471-2148
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pubmed:author | |
pubmed:issnType |
Electronic
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pubmed:volume |
10
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
364
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pubmed:meshHeading |
pubmed-meshheading:21110847-Amino Acid Sequence,
pubmed-meshheading:21110847-Animals,
pubmed-meshheading:21110847-Evolution, Molecular,
pubmed-meshheading:21110847-Homeodomain Proteins,
pubmed-meshheading:21110847-Mammals,
pubmed-meshheading:21110847-Molecular Sequence Data,
pubmed-meshheading:21110847-Phylogeny,
pubmed-meshheading:21110847-Pseudogenes,
pubmed-meshheading:21110847-Sequence Alignment,
pubmed-meshheading:21110847-Sequence Analysis, Protein,
pubmed-meshheading:21110847-Synteny
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pubmed:year |
2010
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pubmed:articleTitle |
A family history of DUX4: phylogenetic analysis of DUXA, B, C and Duxbl reveals the ancestral DUX gene.
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pubmed:affiliation |
Centre for Genetics and Genomics, School of Biology, The University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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