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pubmed-article:21073953pubmed:abstractTextBlockade of T cell costimulatory molecules represents a promising new method of attenuating donor-reactive T cell responses to promote graft survival following transplantation. However, recent studies in murine models have shown the presence of an initial high frequency of naïve donor-reactive T cells may render this strategy ineffective.lld:pubmed
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pubmed-article:21073953pubmed:copyrightInfoCopyright © 2010 Elsevier B.V. All rights reserved.lld:pubmed
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pubmed-article:21073953pubmed:articleTitleCD28 blockade induces division-dependent downregulation of interleukin-2 receptor alpha.lld:pubmed
pubmed-article:21073953pubmed:affiliationEmory Transplant Center and Department of Surgery, Emory University, Atlanta, GA 30079, United States. mandy.ford@emory.edulld:pubmed
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