Linked Life Data

21053919

Source:http://linkedlifedata.com/resource/pubmed/id/21053919

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
23
pubmed:dateCreated
2010-12-1
pubmed:abstractText
Four types of water-soluble quantum dots (QDs) grafted with different organic coating layers were fabricated, and their sensitivities for hypochlorite/hypochlorous acid (HClO) were examined. It was found that QDs with HClO reactive (methylamino and sulphide groups) coating layers exhibited a protective effect on HClO quenching of QD fluorescence, whereas QDs with hydrocarbon and carboxylate coating layers showed least protection to QD fluorescence quenching by HClO and, thus, has the highest sensitivity for the detection of HClO. The QDs with carboxylate coating layers (QDs-poly-CO(2)(-)) was successfully applied to the quantification of HClO in tap water. The excellent selectivity of the QDs-poly-CO(2)(-) toward hypochlorite against other reactive oxygen species allowed us to monitor myeloperoxidase activity. Finally, the QDs-poly-CO(2)(-) was also used for the detection of hypochlorite in HL60 cells by fluorescent imaging. Hence, QD-poly-CO(2)(-) exhibits great promise as a selective and sensitive HClO probe in chemical and biological systems.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
1520-6882
pubmed:author
pubmed:issnType
Electronic
pubmed:day
1
pubmed:volume
82
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
9775-81
pubmed:meshHeading
pubmed:year
2010
pubmed:articleTitle
CdSe-ZnS quantum dots for selective and sensitive detection and quantification of hypochlorite.
pubmed:affiliation
Department of Chemistry, National University of Singapore, 3 Science Drive 3, Singapore 117543, Republic of Singapore.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't